Health Care

Scientist Discover New Human Organ

Scientist Discover New Human Organ

Because the spaces form a fluid-highway linking tissues and organs, it may also explain why some cancers, if they invade the spaces, spread more quickly than others.

The interstitium appears as series of spaces, supported by a meshwork of strong collagen and flexible connective tissue proteins. "For a body part to officially become an organ, a consensus would need to develop around the idea as more researchers study it", study author Dr. Neil Theise, a professor of pathology at New York University Langone School of Medicine, told Live Science. The method now used to study tissue involves samples being sliced thinly and then treated with chemicals. The "fixing" process allows doctors to observe vivid details of cells and structures but drains away all fluid.

While researchers not involved in the study agree that the interstitium likely plays diverse roles in the human body, they are reticent to call it a new organ. "In sum, while typical descriptions of the interstitium suggest spaces between cells, we describe macroscopically visible spaces within tissues-dynamically compressible and distensible sinuses through which interstitial fluid flows around the body". The presence of these fluid-filled spaces should also be confirmed by other groups, he added. In 2017, an organ known as the mesentery, which was previously believed to be just fragmented structures in the digestive system, was officially confirmed as a distinct organ. As their research unfolded they discovered the system drains fluid into the body's lymphatic system.

The interstitium stretches throughout the human body and is actually bigger than the skin, comprising 20 percent of the body's volume. It could be the interstitium that has to be breached by the cancer cells in order for them to spread he said. Researchers have known about the "interstitium" - the tissue between organs and vessels in the body - for a long time. This network of channels is present throughout the body and works as a soft, elastic cushion, protecting the organs from external shocks as the body moves. It offers a microscopic view of living tissues instead of fixed ones.

This study is based on a newer technology, where a camera is snaked down the throat with a laser that lights up tissue and patterns.

In 2015, endoscopists Petros Benias and David Carr-Locke, then working at Mount Sinai Beth Israel Medical Center in NY, were investigating a patient's bile duct for signs of cancer, using a new technique called confocal laser endomicroscopy that allows for close examination of living tissue. The pair were investigating patient's bile duct, searching for signs of cancer.

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For their latest studies, the team used a freezing technique to prepare surgically obtained tissue specimens from cancer patients in such a way that the interstitial compartments weren't disrupted.

"Can we detect [disease] earlier by sampling fluid from the space?". "But it was only when we could look at living tissue that we could see that". "The more tissues I saw, the more I realized it's everywhere", he said.

What was once thought to be dense, connective tissues running all throughout the body has now been found to be a network of fluid-filled compartments that may act as 'shock absorbers'. They wrote in the study that they observed spaces where fluid accumulates.

The research appears in the journal Scientific Reports.

Previously, physicians had a somewhat nebulous understanding of the interstitial space, Nathanson said.